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Chapter 1447 1484 At least 20% of the articles are unreliable

"No...as for it." Xiao Kai was startled by Zhou Congwen's rebellious statement.

Textbooks, that's textbooks.

Zhou Congwen sighed, "Whether it is classical physics, relativity, or quantum mechanics are constantly being subverted. This is science. Although our medicine relies on more experience, it is also considered science. As for what is right, who knows?"

"Professor Zhou, are there any examples?" Xiao Kai asked carefully.

Wang Xueteng's ears stood up unconsciously.

She didn't believe what Zhou Congwen said, because Wang Xueteng knew that Zhou Congwen and Mr. Huang had not had much time to contact each other, so where did he say so much?

This ascetic man was talking nonsense again. How could he justify himself this time? The textbook is wrong? Zhou Congwen can really talk nonsense.

"For example, the high-energy phosphate bond of ATP provides energy, Dean Xiao, you know this."

"I know." Xiao Kai tried hard to recall the biochemistry he learned when he was in school, but he had little impression.

In clinical practice, biochemical knowledge is rarely used. No matter how good the memory is, it seems that it is not good for people. After all, it was a long time ago to learn high-energy phosphate bonds.

"Then let me ask you one thing, how many ATP can a glucose molecule be completely oxidized?"

Xiao Kai was stunned.

This problem is simply unpopular and has something to do with medicine, but it is not available in clinical practice.

He immediately thought of Mr. Huang, Zhou Congwen just described. Shouldn’t there be a standard answer to such objective questions?

Xiao Kai frowned and pondered.

"In the cell, after 1Mol of glucose is completely oxidized and decomposed, about 1161kJ of energy can be stored in ATP. The high-energy phosphate bonds for forming ATP require 30.54kJ/mo energy, so the amount of ATP formed is: 1161/30.54=38."

"This is the answer used in high school textbooks, there are 38."

"What then? Professor Zhou." Xiao Kai asked.

"The biochemistry courses in universities have their own algorithms." Zhou Congwen said, "Glycolysis: 1G-2ATP+2NADH+2H++2Pyruvate

=2+2×2.5=7ATP.

Tricarboxylic acid cycle: 2 pyruvate - 25ATP + 6CO2 + 4H20 If malic acid shuttle is performed, it will not reduce energy. It is still 32ATP. 3 phosphate glycerol shuttle will be performed in the brain and other parts to reduce 2 molecules of ATP, and finally produce 30ATP.

“That is, the biochemical textbooks of universities overturned the statement in high school textbooks.”

"But are there 38 ATP pairs, or 30 or 32 ATP pairs?"

Xiao Kai was silent. He had no impression of these words at all, but he remembered some of the malic acid shuttles and 3 phosphate glycerol shuttles.

When I was in school, I didn’t notice that there was a difference between the biochemistry classes in the third grade of college and the high school textbooks.

Professor Zhou is really like this. Why do he remember this kind of thing so clearly?

"Don't say I'm just messing around. We often use blood pressure in clinical practice. The normal range of central venous pressure has been adjusted many times within ten years alone. The same isotonic dehydration is the same. I have seen at least three versions. " Zhou Congwen shook his head, "Let's talk about this, let's talk about it, it's better for interns, and many children are not enlightened."

Zhou Congwen paused for a moment and continued, "The data in the textbooks are constantly adjusting, so why bother the children."

"Professor Zhou, when did you get the clue?" Xiao Kai asked.

"In the Third Hospital of Jianghai City, Wang Chengfa opened the secret when he used his medical record." Zhou Congwen said with a smile.

In the previous life, it should have been the possession of the postoperative system; in this life, it should be the moment of rebirth.

It is nothing wrong to say that Wang Chengfa used a medical record clip to break the hole.

However, there is no way to say such a thing. Zhou Congwen immediately said, "The boss I asked about how much AP glucose produces. I asked some time ago and was scolded by the boss."

"Oh?" Xiao Kai immediately became interested.

"What did Mr. Huang say?"

"The boss draws a picture to explain it to me." Zhou Congwen remembered that when he was a young man in his previous life, he met his own boss and asked this question.

The boss's answer made him realize that the system is not omnipotent.

"How to say it?"

"The boss said that when mitochondria oxidizes in the end, there are two shuttle routes, one is to generate 2.5 atp and the other is to generate 1.5 atp, which causes the difference in the number of atp generation.

During anaerobic fermentation, 2 atp was consumed, but during one anaerobic fermentation, there were two substrate-level phosphorylation, generating 4 atp, and net generating 2 atp.

So any steps in the body, including pyruvate cycle, pyruvate generation acetyl-CoA, tricarboxylic acid cycle, etc., are all used to generate atp, although they are all preserved in the form of NADH and FADH."

"..." Xiao Kai was speechless.

Do this pair of weird masters and apprentices usually talk about these things?

Who would care about how much A can be produced by a completely oxidized glucose? This has no guiding significance for clinical treatment, but it is like doing scientific research.

But Xiao Kai immediately thought of the way Huang Lao and Zhou Congwen worked tirelessly to study new techniques every day. Perhaps this is what clinicians should have.

"The literature is not all right. At least 10-20% of the world's top journals are nonsense, and this is at least." Zhou Congwen said, "It is better to have no books than to believe in books. Even teachers are not good at being good. How can you blame students for your reputation?"

Xiao Kaipin sucked Zhou Congwen's words.

This passage looks messy and scattered, but after careful consideration, I said a lot, not just Director Lei of the gynecology department.

Wang Xueteng remained silent and drove the car speechlessly.

The doctors she has come into contact with, besides Zhou Congwen and Zhou Congwen's medical team, can publish an article starting with China.

SCI? No one would think of the doctors in the Imperial Capital, except for the Imperial Capital.

And what about Zhou Congwen?

I have actually begun to have an "objective" understanding of the world's top journals, and 10-20% of the literature content is wrong!

Logically speaking, Wang Xueteng believes that Zhou Congwen is right. Medicine is a science that always overturns the cognition of predecessors and makes progress.

But on the highway to Jianghai City, listening to Zhou Congwen talking similar words endlessly, this gave Wang Xueteng an illusion that the big boys playing basketball on the school playground were sweating profusely, and the one who played the best actually pointed at the NBA stars.

At the Third Hospital of Jianghai City, Li Qinghua sat in the waiting area of ​​the patient's family and accompanied Li Ran.

Zhou Congwen called and although he was a little unhappy after having dinner and chatting with Zhou Congwen last time, he saw through it and said it out loud. Li Qinghua must do his best to complete the things Zhou Congwen told him.

Moreover, Li Ran also walked out of the Third Court of Jianghai City. He had to take good care of his own soldiers, both in terms of feelings and in terms of reason.

Li Ran was waiting for the CT result expressionlessly, and he didn't even dare to go to the operating room.

Li Qinghua understood this feeling. When he found a small nodule in his physical examination last year, he was the same as Li Ran every day.
Chapter completed!
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