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Chapter 113 Penicillin (3)

Kashkov glared at Zhao Shi, who was about to give Zhao Jingfu the injection, and pointed at him, "You, go out! Are you a doctor? Are you trying to kill him if you do this?"

Zhao Shi pretended not to understand Russian, ignored Kashkov's accusations, and still raised the needle and stabbed it "silly".

Among the Anti-Japanese Allied Forces, Li Zhaolin has the highest position. It is natural that he stepped forward to negotiate. Ma Qian'an acted as a translator. Ma Qian'an's tall figure deliberately blocked Kashkov's view of Zhao Shi and protected Zhao Shi to continue.

Li Zhaolin's attitude was very kind. After all, the Soviet doctors were conscientious in confronting the soldiers of the Anti-Japanese United Army. A large number of wounded and sick were well treated in this hospital. Out of respect and gratitude, Li Zhaolin explained the incident.

"Look, comrade doctor, this is the case. Our Political Commissar Zhao seems to be resistant to sulfonamide drugs. This medicine is not very effective on him, so we try to use penicillin, otherwise we can only watch him die. I don't think you want this, right? We didn't say hello to you, because we were too anxious. We rushed here in a hurry, afraid that we would step late. I apologize to you for this matter."

Li Zhaolin heard Zhao Shi pull the sulfonamide resistance in the car, and learned and sold it now. At this moment, he shook it out, and he had a bit of self-taught style of becoming a doctor after a long illness.

Ma Qian'an blinked in surprise and translated it with added fuel to the fire. He deliberately bit the name of the penicillin drug very heavily.

Seeing that the other party was so polite, Kashkov knew that Li Zhaolin was an important general of the Anti-Japanese Allied Forces and still had to sell his face. He muttered, "You are really, you are taking medicine without the doctor's consent. If you have any trouble, you must be responsible."

Seeing Zhao Shi put away the syringe and knowing that he had completed the injection, Kashkov couldn't make a fuss and screamed, so he could only ask Li Zhaolin to be responsible for the matter.

Li Zhaolin patted his chest and promised that if Zhao Jingfu unfortunately passed away, he would definitely prove the truth and would never trouble the Soviet doctor.

"Oh my God! What did you say? Penicillin?" Kashkov finally realized that it was much later than Ma Qian'an expected. Really, Kashkov was like a whale that had bitten his tail on Saturday and felt pain next Monday, with a similar nerve conductivity as that of a snail.

As a well-known doctor, Kashkov followed the medical** stream. He wanted to read the latest medical papers in the world. He only read the Russian translation of the English magazine "The Lancet" a few days ago. He still had a sense of respect for Dr. Qian En in his mind. He knew that this new drug appeared and that this drug was miraculously effective for the complications caused by Staphylococcus. He knew that the reality of large-scale cultivation of bacteria has not yet been understood. However, how could these Chinese people have it? What channels did they get it? Do they still have connections with Dr. Qian En?

But no matter how you ask, the hateful translator Wang Gu said that he just didn't go to the right path. There was no way, Kashkov ordered the nurse to come quickly, but he excitedly circled a few people like he caught a big fish, watching tightly, and preventing them from leaving.

Ma Qian'an and several others were in tune with each other and suddenly laughed as they looked at each other.

On the way they came, they had already learned about Zhao Shi's work results. The half-can of crystals that Zhao Shi brought out was more than 40 grams. According to each gram, it would be more than 40 grams. Although the estimated active ingredient per gram is 10,000 units, compared with the hundreds of thousands of units per gram and the effective ingredient of millions of units in later generations, it is a little less, but don't forget that there are no staphylococci in the world that produce antibodies, and they have not become smart yet. So even if it is 10,000 units, for these unsmart Staphylococci, it is just a Green machine gun. Without practicing Keanu Reeves in "The Matrix", the end of the game is that corpses are everywhere.

In Ma Qian'an's impression, Pfizer found a way to cultivate strains on a large scale at the end of 1942. Before that, countless biologists of lofty ideals were culturing on a small scale in the laboratory. There was no data to show who could find a record of 4OOG finished products at once. So he asked Zhao Shi, have you found a way to cultivate strains on a large scale?

Zhao Shi replied, people are not really strange things. If you don’t force him, he will be lazy. Just like Professor Fleming, who first appeared in this kind of bacteria, gave up the purification because he couldn’t find the culture medium and missed the relationship with wealth. There is also Dr. Qian En. Although he found a constant temperature method to cultivate a large number of bacteria in the corn solution, these bacteria still cannot produce enough medicine to treat a person. They may not have any sense of urgency in their minds. Unlike our Anti-Japanese United Army, people are dying every day. I feel urgency here. Team Horse, look at my mouth full of bubbles.

Ma Qian'andao, Zhao Shi, can you not sigh at first, run the train and brag about yourself, you should pay attention.

Zhao Shi didn't care about Ma Qian'an's criticism at all, but his expression was indeed a little restrained. He said: Team Ma, these days I used Dr. Qian En's method to cultivate corn culture medium in a constant temperature box. I calculated that it took 30 boxes to extract a medicine after 7 days. Even if the electricity in the diesel motor was not used, ordinary electricity, machine depreciation, electricity bills, and labor costs. The cost of this medicine is as high as 6 o'clock, which is about 2 US dollars. If it is sold, it will also add profits, new drug promotion costs and sales costs, which are very likely to cost 4-5 US dollars. If you don't think about the low output, if it is produced, who can afford it? I'm afraid that one medicine is not enough to cure a person. I don't know that this thing is not a fairy pill, one pill works. Anyway, our army cannot afford it, and the people have no chance. Only high officials can use it, so the market for this medicine is too small.

The cost is so high and the output is so low. No wonder there is no pharmaceutical company producing it. Just investing equipment in the early stage will cost the life of a small pharmaceutical factory.

Zhao Shi suddenly said something that was very disproportionate to his age. War is so irritating! Do you remember that I asked you to buy dozens of large jars and jars?

I can never remember that when Ma Qian'an purchased materials, he did not do everything himself. Only some major equipment or things that needed approval were allowed to come forward. Generally, popular items were handed over to his subordinates.

So what if you have a jar or a big jar?

Zhao Shi continued to talk about himself. Several of us were walking around, and each of us was thinking about how to make more bacteria and more bacteria. Until one day we drank yogurt, Hu Qi thought about the method of fermentation. Through practice, we unanimously believed that we had found a solution. As long as there was a room or warehouse that kept constant temperature, we could use these large tanks to make containers for fermenting this kind of mold. We found that the degree and density of mold growth in the fermented culture medium have been greatly improved, and we have already achieved mass production at low cost. Zhao Shi raised the bottle in his hand and said proudly: This is the result.

During World War II, foresighted leaders were rare. Now that the war has begun in Europe and Asia and gradually revealed signs of world wars, the leaders of these countries did not realize the great significance of this antibiotic. Perhaps they did not care about medical things at all. Perhaps in the eyes of these politicians, a new drug is not as meaningful as an airplane. In short, I have never heard of any country that has begun to spend valuable manpower and material resources to start industrial production.

Among the leaders here, Roosevelt realized the role of new antibiotics, but it was only after the United States joined the war in 1942 that it ordered various pharmaceutical companies to develop industrial production methods. Finally, in 1942, a small company, Pfizer, developed a fermentation method to form mass production.

It has been less than two years for Zhao Shi and Ma Qian'an to freely exhibit batch pharmaceuticals, perhaps even shorter. After mass production can be produced in the United States, Zhao Shi's original handmade method, the output cannot be compared with Pfizer. Ma Qian'an has watched a short film and only remembered a few limited data, including Pfizer's output and output value in 43 years. In a year, Pfizer produced a total of 450,000 units with a output value of 240,000 US dollars (35 USD = one ounce of gold = 31 grams), all purchased by the army. That is to say, each unit is about half a dollar, and the selling price of 1.5 oceans, of course, the price that falls into the hands of the people on the market will increase by many times.

Ma Qian'an muttered, "Stop it, I didn't say it just now, and then asked, "So, has the cost of cultivating bacteria in this way?"

Zhao Shi replied, of course, there is no electricity, no need for so many machines, no need for so many labor, and a lot of money. If you collect mold in this way, the cost of each piece can be controlled at about one ocean. This is what we are doing. We are not doing production, and maybe a professional factory manager can also reduce the cost.

Yes, Zhao Shi's words are very modest and realistic. He can do research and production, and he is definitely not as good as a skilled and efficient factory manager.

In the car, everyone finally decided unanimously that the fermentation method must be kept confidential and confidential. Everyone knows that the value of these life-saving drugs will be leaked and will be lost to a certain level. This is not only a matter of money, but also a matter of enhancing our economic capabilities. For every extra 3o or 5o US dollars, you can buy an extra gun or 1ooo bullet. At this point, everyone has the same idea. Open the secret? That is the idea of ​​a fool. Once it is made public, the powerful enemies will be stronger now. They have the advantage. The new technology will have a greater amplification effect on them than on the weak anti-Japanese army. As the saying goes, new technology will also be obtained, but due to different economic conditions, the role of the strong and weak sides is different. The strong are stronger and grow in a geometric multiple, and the weak can also be improved, but it is linear. Therefore, the disclosure of this technology now is not a blessing to oneself but a cruelty.

For S1 people, we can provide finished products for certain materials and support. We must not leak production methods. We would rather destroy the training room at critical moments than give S1 people to S1 people. Although we can only maintain an advantage for more than a year, this is enough. We will never maintain an advantage for a month.
Chapter completed!
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