Kunshi, Sanqing headquarters.

Just when Ding and Huang were anxious about human clinical trials.

Wei Kang thought of this situation earlier than them.

"It is simply unrealistic to expect the National Health Commission to make changes as soon as possible and promote brain death legislation."

"Firstly, the impact is too great, and secondly, there are too many relationships that need to be coordinated in all aspects."

"It's just a human clinical trial. There is no need for the company to be anxious. We are not waiting for this project to save lives. There is no need to do such a thankless thing."

"After all, in the Chinese cultural circle, the common thinking of the people is that it is difficult to accept the fact that a relative with a warm body and a beating heart has completely died, and it is even harder to accept the fact that a relative who is still breathing is pushed to the operating table for human body surgery.

experiment."

"So even if the death result of brain death is clear, it will be difficult for the public to accept it. If they don't accept it, there is nothing they can do. Body donation is indeed not a popular thing."

"Both the Bon Country and the Sakura Country in the same cultural circle have long made it clear that they have legislated brain death, and the proportion of people donating their bodies is also very low, far inferior to Western countries."

"From this point of view, we have to admit that cultural differences do exist. People in the Eagle Country just need to be more open-minded."

"The acceptance of human experiments in China is very poor. There are a lot of clinical studies, and dozens of cases are often needed. It is difficult not to make people think that they have to cut open the hearts and kidneys of so many brain-dead patients."

"If you rush to carry out human clinical research, I'm afraid you will risk the world's disapproval. Even with Sanqing's reputation, it is estimated that it will be difficult to withstand it, and it may become a dark history. It is difficult, it is really difficult."

After thinking about it this way, there were not many choices left for him.

"It seems that the only way to achieve the goal is to conduct clinical trials overseas and at the same time remove Sanqing from the moral dilemma. Even if we don't go to Eagle Country, we can go to other places, such as Tianzhu, Philippines and other places."

"I read the report submitted by Ding Mian. The highest degree of human-pig organ chimerism is only 92%, and it also contains some pig cells. Although it has been genetically modified, the possibility of immune rejection is very low, but in terms of biological safety

, we still need to take a long-term approach.”

"If overseas clinical trials prove that it is safe and effective, these clinical data will also be recognized in China, and then you can directly apply for Phase I clinical trials in China."

"It seems that overseas clinical practice is not a kind of protection for domestic patients."

Wei Kang thought for a while and quickly made a decision.

"Otherwise, we can simply conduct overseas clinical trials in countries that recognize brain death, and then return to China with the data to apply for Phase I clinical trials."

"It doesn't matter if the domestic progress is a little behind, safety comes first and stability comes first."

"Then the question is, which country should I choose?"

"Eagle Country? Europa? Or Tianzhu?"

"Try the FDA first? I remember that Eagle Country also has some research on xenogeneic organ transplantation. It has a lot of experience in this area and there are many excellent doctors."

At this moment, Wei Kang's cell phone suddenly rang.

When he looked at the caller ID, he immediately smiled.

He said Cao Cao and Cao Cao were here. As soon as he thought about the FDA, an acquaintance came to the door.

"Dear Wei, long time no see. Congratulations to Sanqing for his breakthrough achievements in the field of organ transplantation."

As soon as the call was connected, Andre's familiar voice instantly sounded, which made him feel quite impatient.

The corners of Wei Kang's mouth raised, but he remained calm on the surface: "Thank you for your compliment. This is mainly the result of the hard work of the company's employees. I, the boss, actually didn't participate much, so I feel ashamed."

Andre laughed, exchanged a few greetings as usual, and then quickly got to the point.

"Dear Wei, may I ask how far this project has progressed? Has human clinical trials started?"

"As far as I know, before xenogeneic organ transplantation can enter human clinical practice, there is a threshold that must be crossed, and that is clinical research on brain-dead patients."

Weikang has no intention of hiding it. Whether it has been approved for human clinical trials can be found directly from the official website, not to mention internal information. It is very easy for colleagues to know.

He readily admitted: "This human clinical trial has not yet started, and the preclinical research is currently encountering some problems."

"If you have spent several years in China, you should know that brain death is not recognized here, so it is very difficult to conduct clinical research on brain-dead patients. It is difficult for parents alone to persuade, let alone supervision."

"But I believe it will be solved soon. It's just a little slower. I don't care about the time."

Andre couldn't help but feel happy when he heard Wei Kang's confession. He had learned about China's special situation, so he volunteered to be the intermediary, planning to persuade Wei Kang to conduct clinical research overseas.

In this way, clinical research on Sanqing can proceed smoothly, and patients in Eagle Country can benefit from it as soon as possible.

You must know that some of the financial backers behind him are already very old, and they are eager to see this achievement implemented in reality, and the sooner the better.

After all, if a technology wants to be mature and usable, it requires a lot of practice in the early stage. If the application time can be compressed from ten years to two or three years, it will undoubtedly gain huge benefits.

As for Wei Kang's statement that he didn't care about the time issue, he was directly regarded as being arrogant.

In his mind, for such a major project, Sanqing must have invested a huge amount of research and development expenses. Who doesn't want to get returns as soon as possible?

Because some regulations have blocked the progress of research and development, I must be very anxious, but for the sake of face, I can only say that I don’t care.

Such a reaction is very reasonable, and that's why he came here.

After many years of dealing with each other, he believed that he still understood Wei Kang's character and thoughts very well. When encountering difficulties, the other party would not directly seek help from outsiders. At this time, friends like him were needed to take the initiative.

"The character of Chinese people is like this. No matter how straightforward they are, they are more or less concerned with saving face."

Thinking of this, Andre smiled slightly, showing an expression of victory.

"Wei, our friendship has always been extremely deep over the years. As a friend, when I see you encounter difficulties, I naturally cannot sit idly by and do nothing."

"In fact, in our Eagle Country, brain death is a very normal thing. A medical team from the Mayo Clinic implanted a pig heart in a brain-dead patient. Although the patient did not survive, follow-up research did not

We have a lot of experience in this area."

"Believe me, if you are willing to come to Eagle Country for overseas clinical practice, there will definitely be a lot of hospitals rushing to cooperate with you, and the FDA will give you the green light all the way."

"Our laws and regulations in this regard are also very mature and reliable. Everything is based on the interests of pharmaceutical companies. Oh, it should be said that everything is based on the development of medical research."

"So, you really don't want to consider overseas clinical practice?"

"That's for sure. Your Great Eagle Empire's experience in human experiments is absolutely unparalleled in the world. It can't even be described as rich. If you dare to claim to be second, no one will dare to claim to be first." Wei Kang thought in his heart.

He complained silently.

Although he had already made up his mind, in the face of Andre's warm invitation, he still pretended to think for a moment and looked like he was in a dilemma.

"Andre, what you said makes sense, I almost got excited, but my subordinates found a new way, which is to directly connect the human kidneys in pigs to the blood vessels of brain-dead patients, and do extracorporeal dialysis first.

How long can it last?"

"If this method can be proven to be safe and effective, it may be able to push clinical research a step further in China."

"So I plan to see the results first before making a decision. As my friend, you should be able to understand."

Andre's heart was burning, but he still said calmly: "As a friend, of course I will understand and fully support your decision."

"However, let me kindly remind you that it is good to be prepared for anything. You can apply for domestic clinical trials while preparing for overseas clinical trials in advance. After all, you cannot give up on overseas markets. What do you think?"

When he said this, Wei Kang followed suit and said with a smile: "This is a natural and reasonable suggestion. I will definitely listen to it."

"I will ask the Yingguo branch of Sanqing to submit a clinical application to the FDA soon."

Andre nodded with great joy: "That's great, then I'll wait for your good news. If you have any questions, I'll be at your service at any time."

****

At the same time, outside the ICU ward of Kunming First People's Hospital.

An old woman with gray hair was crying her heart out, her tears falling uncontrollably. Next to her, a man in his early 30s was wiping away his tears while patiently persuading her.

"Mom, Dad is in this situation, so you should just accept it and accept it."

"The doctors said he's brain dead, but it's really hopeless. Don't cry too hard, or you'll destroy your body."

After saying that, he winked at his wife, and saw that the other party supported the old mother with understanding, and then walked towards Director Cui of the intensive care unit on the side.

"Director Cui, look at my dad's condition, how long can he stay in the ICU?"

Director Cui stood aside for a while. He finally found a fresh brain-dead patient. In order to complete the task assigned by Director Fang, he had to bite the bullet.

"Your dad's medical certificate has come out. He is in a deep coma without any reaction. His brain stem is dead, his brain electricity has disappeared, and his cerebral blood flow has stopped. He is diagnosed as brain dead. There is no point in continuing treatment, and there is no way to save him."

Director Cui considered it and said: "Of course, if the family wants the patient to continue to stay in the ICU and maintain his physical condition, it is not impossible, but the cost will be relatively high."

"I personally suggest that family members should act according to their ability, because the survival period of most brain-dead patients is about a week and rarely exceeds two weeks. Although the ventilator can keep the patient breathing and heartbeating, over time, the blood pressure will not be maintained.

His body functions completely failed and he died."

The man frowned and said with a somewhat irritated look: "Your doctor has said these words several times, and my ears are ringing. It's not like I don't know what brain death is like."

"The problem is that I accept it, but my mother doesn't accept it. As soon as I said I wanted to extubate, she started to have a life-and-death fight with me."

"Damn it, I can't be accused of being unfilial and make my family uneasy and make my mother hate me for the rest of my life."

Director Cui nodded: "The emotions of the family members must also be taken into consideration."

After being in the ICU for a long time, he had seen a lot of human emotions, and he knew that haste makes waste, so he did not immediately persuade the other party to do human experiments, but waited slowly.

The other party will definitely ask the most critical question, he is sure.

Sure enough, the man hesitated and asked: "Well, if my dad stays in the ICU until he dies, how much will it cost?"

Director Cui pondered and said: "If you stay in the ICU and receive necessary cardiopulmonary support, blood pressure support, and nutritional support, you can probably last for about a week, and it is extremely unlikely that you can last until two weeks."

"The daily cost of medicines and equipment is about nearly 30,000 yuan, and a week is about 200,000 yuan. If you insist on it for two weeks, it will be nearly 50,000 yuan."
To be continued...