Then the question is.

After decades of clinical work, these old Taishan people have never thought about the cause of gastric ulcers. They have never thought about one day taking out a microscope and carefully observing whether there are some bacilli on the gastric mucosa specimen?

Why can a general internal medicine graduate student in Australia find problems that they have never discovered?

After all, this is just light scientific research.

If the medical foundation is not laid well, it is actually difficult to improve the clinical diagnosis and treatment level.

You know how to treat it, but you have to treat why you use this medicine and how this disease occurs? I didn’t understand this clearly, and I only know how to use it, and my level is limited.

Even if the "guidelines" issued by domestic medical associations decades later, to put it bluntly, they are copied from foreign guidelines, and there is almost no clinical experience that we have innovated ourselves. This is really a matter of blushing.

This is where we suffer. We know how to do it, and we are quick to do it, but often we can't explain why we do it. We only know how to follow others and follow other people's batons.

It is almost impossible to award the Nobel Prize in Physiology or Medicine to clinicians, which shows that foreign countries are the places where basic medical research is truly valued.

This Helicobacter pylori study also falls within the scope of basic medical research, so here is the reason why Chen Xia won the Nobel Prize at the same time in his previous life.

After the director of the Science and Education Department introduced the leaders and medical experts, the following is the main topic, and Chen Chun will be the main speaker.

Chen Chun took a deep breath, and on the surface he was full of confidence, but in fact he felt very nervous.

Several old professors were also quite surprised. It turned out that the first author of the Helicobacter pylori paper was so young. So my suspicion also aggravated a little, and I planned to ask carefully in a while.

The old intellectuals can't tolerate sand in their eyes.

Zheng Haidong also came here this time, because he was doing the research and reverse engineering of proton pump inhibitors for the key to the treatment of Helicobacter pylori, so the Provincial Hospital also asked him to go with him.

He looked at his girlfriend who was very confident on the surface, and he felt so proud.

Chen Chun turned on the slide projector he brought in and began to explain. Of course, being humble first is a necessary process, and the Chinese are so polite.

Or... hypocritical...

"We occasionally found an unknown bacillus in tissue specimens of patients with gastric disease. For this reason, we specially extracted gastric mucosa specimens from inpatients in the Department of Gastroenterology, including the First Hospital, Second Hospital, Third Hospital, Fourth Hospital, Fifth Hospital, Yuezhou People's Hospital, and Yuezhou Second Hospital.

A total of 200 samples of patients with common gastritis were extracted, and 140 cases of this unknown bacillus were found, with a proportion of 70%.

There were 200 specimens of gastric ulcer patients, and 190 unknown bacillus were found, with an average of 95%. Among them, the infection rate of Helicobacter pylori in patients with duogastric ulcers was as high as 90% to 100%, and gastric ulcers were 80% to 90%.

50 cases of gastric cancer patients were extracted, and 44 cases of unknown bacillus were observed, and the proportion reached 88%.

In other words, this unknown bacillus exists in most patients with stomach disease. So is the existence of bacillus and the occurrence of stomach disease? Now we are conducting this step of research.”

Professor Sang Caihua from Peking University Third Hospital raised a question:

"You just discovered the existence of this unknown bacillus, but is there an inevitable connection between the existence of this bacillus and stomach disease? This may not necessarily be equated, right?"

Chen Chun nodded and replied very seriously:

"Professor Sang's question is also the question of our research team, and the purpose of the Xiangjiang Pumpkin Vine Company entrusted us to conduct further research.

We found that this is because the harmful substances produced by Helicobacter pylori can damage the gastric mucosa and cause gastric mucosa dysfunction. One of them is ammonia, the chemical name NH3. When ammonia directly contacts the gastric mucosa, it will cause mucosa bleeding.

Our experiments have shown that when Helicobacter pylori comes into contact with gastric cells, the cells will stop working one after another. After 24 hours, the toxins released by Helicobacter pylori lead to damage to gastric mucosal cells, which in turn produces white vacuoles, causing gastritis.

At the same time, Helicobacter pylori will also produce a large number of highly active urea enzymes, which will decompose urea into ammonia and carbon dioxide. Ammonia can neutralize gastric acid, so that this bacteria can survive in the stomach with high acidity.

The accumulation of ureaase and ammonia can also damage the gastric mucus layer and mucosal cells, destroy the muco-bicarbonate barrier, and cause protons to flow back to the mucosa, thus leading to the occurrence of peptic ulcers.

If Helicobacter pylori persists and the inflammation continues, and the human body is under pressure from the external environment, the mucus that protects the stomach wall cannot function normally. As a result, gastric acid causes damage to the gastric mucosa and becomes gastric ulcer. The ulcer will cause gastric bleeding, which will worsen into gastric holes, and eventually lead to gastric cancer."

Professor Xu Guangzhou from Union Hospital was shocked:

"So, your research has not only discovered the existence of this unknown bacillus in different patients with gastric diseases, but also has studied the principle of the pathogenicity of this bacillus? So in-depth?"

Several other experts also discussed it and found it too incredible. After all, the topic was reported to the Ministry of Health, and it has only been more than two months since it has been reported.

In such a short time, with the scientific research capabilities of two hospitals and one university, they could have already studied to such an extent that they could not imagine.

Which medical research does not take years or even decades of unremitting efforts, a lot of money and a large number of researchers to achieve some results.

Could this laboratory of the First Hospital of the Provincial Hospital and Yuezhou People's Hospital be cheated?

If Chen Xia heard their conversation, he would definitely answer in his heart:

"Isn't it a cheat? These theoretical studies have long told Chen Chun that what she wants to do is not exploration and research. She just repeats this step, so how can she not be happy?"

Chen Chun nodded again and answered questions patiently:

"Yes, Professor Xu, the reason why our research progress is so fast is based on a series of research results that Xiangjiang Pumpkin Vine Company has already conducted, which is equivalent to us standing on the shoulders of giants."

Everyone turned their eyes to Chen Shuqin, wondering why such an epoch-making research project was not in Xiangjiang, but instead went to the mainland to seek cooperation.

Some people who are highly vigilant and have a brain to class struggle are in their minds, is there any conspiracy here? Capitalism is not going to die.

Chen Shuqin is such a smart person.
Chapter completed!