Font
Large
Medium
Small
Night
Prev Index    Favorite Next

Chapter 60 Study of Coenzymes

The reason why Yang Rui's laboratory is affiliated and purchased equipment through the Xibao Meat Connection Factory is that there is a biochemical pharmaceutical team under the Xibao Meat Connection Factory.

Some people may find it strange that there is a pharmaceutical workshop in a meat-to-meat joint factory, but in fact, until the 1990s, most biochemical pharmaceutical factories in China were located in meat-to-meat joint factories.

This is determined by the nature of the biochemical pharmaceutical factory. Primary biochemical pharmaceuticals are produced using animal organs. If you want fresh animal internal organs, but do not have good means of preservation and transportation, and if the factory is not set up in a meat-in-one factory, where can it be set up?

At this time, the biochemical pharmaceutical factory was not called a biochemical pharmaceutical factory, but was generally called an organ biochemical factory or an organ biochemical workshop. It was not large in scale. Xibao Meat Connection Factory only had a team of more than ten people. If it was based on the workshop, it was already a top-ranked factory in China.

Journals and books related to biopharmaceuticals are either called "Organ Biochemical Pharmaceutical" or "Animal Biochemical Pharmaceuticals". The microbial fermentation and plant cell culture methods commonly used in later generations are still under research, let alone chemical synthesis methods, which are always the most difficult and last popular method.

There are many organs that can be used in pharmaceuticals. The pancreas can extract insulin, pancreatic enzymes, the heart can extract coenzymes, and the brain can extract cholesterol... In 1982 years, all biological products are expensive and have no worries about sales.

However, the biochemical pharmaceutical team of Xibao Meat Connected Factory is not valued. Their most profitable project is to export white meat to Europe, earning millions of dollars in exchange for every year, which is also the capital of the factory leaders.

In comparison, although the products of organ pharmaceuticals are valuable and have a very amazing cost. Using the methods of the 1980s, a kilogram of organs may only extract dozens of milligrams of products, and other solvents and materials are consumed during this period, which is not worth the cost. Moreover, the biochemical products of Xibao Meat Factory are relatively common in the 21st century, and the biochemical pharmaceutical teams of Xibao Meat Factory cannot make them. With their technology, they are not cheaper to do what others can do, and they cannot do what others can do.

Of course, there is no such problem in Yang Rui.

After 30 years of development, he used later laboratory methods and the output was higher than that of the biochemical team of Xibao Meat Converged Factory. Of course, the scale of the biochemical team of Xibao Meat Converged Factory is actually the size of the laboratory, but there are only a few more people.

Yang Rui is not planning to sell biochemical products directly to make money. These things are currently in a state-wide monopoly model. It is troublesome to make a lot of money in an individual and it is also very tiring. Continuous production is that long-trained workers are prone to making mistakes, let alone him and a group of students.

It is probably feasible to get honors, but Yang Rui cares the least.

Rather than making less money for honor, Yang Rui is more willing to lay some preparations for some papers.

When he was a graduate student, he spent most of his time searching for papers for his teachers. Usually, if the tutor makes a list, he would have to check the information for a week. It would be impossible to integrate the journals and books he had read, but he had to scan it all over.

In this way, these papers are now reflected in his mind.

Yang Rui just chooses some simple ones to re-do the experiment and then rewrite it.

As for how simple it is to make your small laboratory work, Yang Rui’s way of judging is the price of experimental equipment.

The simpler the equipment, the better, the less instruments are used, the simpler the experiment, the better, and the easier it is to buy raw materials.

After screening this way, Yang Rui selected related research on coenzyme q10.

Enzymes are the catalyst for organisms, and coenzymes are the so-called "second substrate" that assists the work of enzymes. Common coenzymes include vitamin b1, vitamin b2, folic acid, etc. These very cheap coenzymes in later generations were produced by chemical synthesis. The cost of a bottle can be reduced to a few cents, but in the beginning, they were still obtained by extraction. For example, the folic acid that all pregnant women need to eat was originally isolated from spinach leaves and was named after it.

From this point of view, the so-called diet therapy in China has some significance.

Coenzyme q10 is a late coenzyme discovered and was first extracted from animal heart tissues. Its research history is very long.

As early as 1974, Japan's Eisai Pharmaceutical Factory sold it as a heart disease drug and attracted the attention of many biologists. Therefore, in the next few years, three special seminars were held in one breath to conduct extensive research on its biomedical and clinical applications. China also made coenzyme q10 in 1976.

Until Yang Rui traveled through time, Coenzyme q10 was still a research hotspot. Biologists were still studying its biomedical and clinical applications, and pharmaceutical companies were still studying its production methods. Although each research has made a lot of progress, Coenzyme q10 is not a cheap biochemical product.

In 1982, Coenzyme q10 was naturally more valuable, both in products and research papers.

It is precisely because 30 years later that coenzyme q10 is still a hot topic in research that Yang Rui has been able to read many related papers. As long as the experimental equipment is in place, he can copy a basket of articles.

In fact, experts and professors at home and abroad who have been studying coenzyme q10 for a lifetime are all over the floor. If you cut off your ears, you can almost fill a basket. There are not many more Yang Rui, and not many less him.

Adhering to the idea of ​​low-key accumulation, Yang Rui first purchased beaker, flask, triangular bottle and other instruments in the name of the school, ethanol, propanol, butanol and other reagents, and then directly ordered two batches of coenzyme q10 refined products from Pingjiang Biochemical Pharmaceutical Factory in the name of the biochemical pharmaceutical team of Xibao Meat Factory.

He is planning to write an article on how to more accurately determine Coenzyme q10. Compared to directly producing Coenzyme q10, this article is not weak, but it will be simpler.

While waiting for the goods to arrive, Yang Rui began to tutor the members of the Ruixue Group and selected his own experimental assistant.

Li Tieqiang and others will continue to come to the classroom to listen to the class, but they can no longer get the test paper for free. Yang Rui will not correct the test paper for them, and will not make targeted course tilts.

For students who have not enjoyed this kind of treatment, it may be difficult for them to understand the so-called tilt effect, but for Li Tieqiang and others who have enjoyed special treatment, they immediately felt the change.

It has become difficult to improve grades.

They couldn't tell the reason, but they were even more panicked.

Someone took advantage of the evening to find Yang Rui, hoping to join the Ruixue Group again, but was blocked by Cao Baoming, who was in the same room, without hesitation.

Li Tieqiang and Wang Wanbin also tried to chat in the cafeteria, but were still rejected without hesitation.

At the same time, the courses of Ruixue Group have gradually improved from reviewing junior high school and focusing on high school to real high school review.

More difficult questions and more complex review routes further widen the distance between Ruixue Group and other students.

At this time, Li Tieqiang and others regretted even more, but they were just helpless.

Yang Rui had too many cards in his hand that he completely blocked them without saying anything he did.

And the more dull the handling, the more angry it is.

Li Tieqiang and Wang Wanbin simply pulled over a dozen people, organized their own study group, and then studied hard, encouraged each other, trying to surpass the Ruixue Group.

However, they are all old students who have been working hard for two or three years. If the old method is useful, why do they reread it year after year?

What's more, members of the Ruixue Group study diligently in a more scientific curriculum plan, and the gap between the two sides will only widen, but will not narrow.

A week later, when Yang Rui's first batch of simple instruments ordered were delivered, there were only two or three people left in the newly established study group, and they were dead in name only.

More people have focused on this laboratory.

In the history of Westborough Middle School, there has never been a laboratory configuration.

Even Principal Zhao couldn't help but come to this small house next to the garden, observing and touching the simple flasks, burettes, ph test strips and other objects one by one, and sighed: "You'd be fine if you came to school two years ago, and Lao Tan might be able to stay."

Lao Tan is a chemistry teacher at a university. Because of the best reasons, he ran to Xi County and was later protected by Principal Zhao. However, in the year Yang Rui was in high school, Lao Tan resurrected and returned to the city.

Yang Rui disagreed with Principal Zhao's feelings and said with a smile: "The current configuration of this laboratory is not as good as that of a middle school in the provincial capital. Even if it is fully equipped, it is not as good as a laboratory at Hedong University. Teacher Tan cannot do an experiment even if he stays behind, and he can only waste his whole life."

"Why is teaching a waste of time?" Principal Zhao knew that he was right, but he was still unwilling to admit it. He shook his head and said, "I think your laboratory is good enough. You have whatever you want. There are many bottles and jars than No. 1 Middle School. Is there any experiment that can't be done?"

Yang Rui smiled and said, "The laboratory of No. 1 Middle School is for teaching purposes. What's the point of competing with them? Moreover, in terms of assets, this laboratory is only worth 1,000 yuan. Why does the laboratory of No. 1 Middle School cost tens of thousands of yuan?"

"Bad. They received a batch of experimental instruments in 1978, otherwise they would be poor now." Principal Zhao said, turning his face and rubbing his hands, "Or, let our school students come to your laboratory to do experiments?"

Yang Rui spread his hands and said, "It takes materials to do experiments. If you are willing to pay for funds to buy reagents or something, I can do it for free."

Principal Zhao was stunned and asked, "How much does the materials cost?"

"It costs a few cents per person at a time. It depends on what kind of experiments it takes. The average 2 cents is needed." The prices in the 1980s were cheap, and experimental consumables were not cheap.

Principal Zhao quickly made up his mind. There were more than 400 people in the school who did an experiment once a month and received at least 100 yuan in funding. Four months a semester, it would cost four or five hundred yuan.

After reaching this result, Principal Zhao immediately changed his words: "It's too troublesome to do experiments. It's just a room that is so big... let the students visit for free."

Yang Rui really wants to say, can free visits make the room bigger?

However, looking at the curious appearance of the classmates around him, Yang Rui couldn't help but soften his heart and said, "Let's just visit. However, if you only visit for free, I will not deliberately arrange the experimental content. It is up to me to explain or not, and the visit discipline must also be listened to me."

"no problem."

"Don't follow the class when visiting. If you want interested students to sign up, I will notify them of the time. This will probably reduce the pressure on the visit."

"no problem."

"The students who came to visit wanted to help me clean the laboratory and clean the experimental instruments."

"no problem."

"Then let it be. If I am really interested, I will find an opportunity to arrange for them to do the experiment in person." Yang Rui did not wait for Principal Zhao to speak, and then said: "There can't be too many people. The school has no funds, and I don't have them either."

If you really want to learn something through experiments, it is at least possible to operate once every half month. It costs 1,000 yuan in one semester, and 2,000 yuan in a year, and Yang Rui can't afford it.

Principal Zhao nodded without hesitation and then made his own request: "If someone comes to visit in the future, you have to say that the laboratory belongs to the school."

"Whatever, the instrument is under my name anyway." Yang Rui still has an invoice in his hand.

Principal Zhao ignored Yang Rui's Xiaojiu and touched his beard and said, "Shengli Middle School paved a cinder road last year. Dong Gouzi invited me to visit twice. I have to recruit this venue."

"You have to notify someone to visit in advance, otherwise don't blame me for the locking of the door." Yang Rui threatened a little. He actually didn't care that someone would come to see him. Writing papers is famous, and displaying laboratories are also famous.
Chapter completed!
Prev Index    Favorite Next