"This is the first priority project. My laboratory has been established for several years, and this is the most important project." Yang Rui convinced everyone in the laboratory and wanted to persuade lawyers who rushed over from Hong Kong.

Of course, the lawyer collects money and has to work no matter what, but whether he understands the importance of the project also determines his working style.

A big-name lawyer can make money anywhere, and he will be like a taxi driver on a rainy day. A simple patent with no profit can be made easier. This kind of patent may expire if you encounter a lawsuit challenge in your life. The patent that Yang Rui expected is time-consuming and labor-intensive. If you want someone to help you do it seriously, you have to prove that your patent is worth it.

Lawyer Yue Ting was very professional and listened carefully with two assistants. He has been a patent lawyer for more than 30 years, and he graduated from the Department of Physics of the University of Hong Kong. His science background has brought him on the path today. Yang Rui deliberately said it simple, so he can understand most of the content.

In about half an hour, Yue Ting proposed to watch an X-ray.

DNA cannot be seen with the naked eye, nor can it be seen by ordinary microscopes. In fact, it is still idle to see it, and you don’t know it.

The DNA of 28 base pairs cannot be answered if you ask it "Who are you?"

To prove the success of PCR, hybridization signals on X-rays must be used.

But Yang Rui first looked at another company lawyer next to him.

The company lawyer also came from Hong Kong, but he belonged to the company lawyer whom Huarui Company had signed a long-term contract with him, and belonged to Yang Rui's own people. After the latter nodded, Yang Rui went to get an X-ray.

In fact, there is nothing to hide. This thing belongs to the professional category and cannot be copied.

The reason why Yang Rui re-done the experiment was to have these seemingly useless proofs.

Otherwise, he would just copy the paper.

However, if you just copy a paper, you cannot pass one academic review after another.

Many papers that change the world are short - Tu Youyou's Nobel Prize-winning paper is called "A New Type of Sesquiterpene-Artemisinin", signed by the Artemisinin Structure Research Collaborative Group, with only one page in the full text. The DNA double helix written in each student's textbook also won Watson and Crick the Nobel Prize, with only half a page in the full text.

A long paper is rare, and such a short paper is also rare.

At least, it is difficult to copy, and applying for a patent cannot be like a paper.

Applying for a patent is a chatterbox, and it comes from the number of more.

In order to apply for a patent, some large companies will list hundreds of parallel patents, all of which are to protect the core patents in the middle.

Therefore, many large companies have tens of thousands of patents a year, but they don’t really have tens of thousands of patents. It would be great if they could have a thousand. The rest are patents of supporting actors.

However, the patent of the supporting actor must be written carefully, which takes time for lawyers and time for patent offices. In the final analysis, it costs money.

And it's very expensive.

This is especially true for mainlanders in 1984.

Yue Tingxin calculated the number and shook his head in his heart.

Of course, he would not say to Yang Rui, "There is no need to get patents like this in your research." If he was a white man, he would make money without saying anything.

Facing Yang Rui who is in mainland China, Yue Ting was interested in saving some money for Yang Rui, and he felt it was too troublesome. He thought about it and said, "I understand what you said just now, but I think the cost is a bit too high, especially what you ask for, you have to apply for multiple patents at one time and apply for protection patents. The cost is not small. In the calculation, it will cost at least millions of dollars. Moreover, because of the salary of other lawyers, the amount of this part cannot be determined, only a lot or a lot."

On the one hand, he was scaring Yang Rui, and on the other hand, he was telling the truth. If he followed Yang Rui's request, he would have to pay a fee of millions of dollars, and it would not be much less.

If you encounter a patented submarine, you have to go to a lawsuit.

And if you want to make a patented submarine by yourself, you have to spend a lot of money.

Patent barriers have always been something that big companies like. When doing this in small companies, they can only do it with confidence, which is a self-defense behavior.

Yang Rui conducted a series of patent application activities for the patent of Coenzyme Q10, but the requirements at that time were more than one order of magnitude different from those now. The strength and price of the lawyers they hired were the same.

However, Coenzyme Q10 is only a market of 1 billion US dollars, and the profits assigned to Jielikan are 1 billion US dollars, and the ones assigned to the patent owner are 1 million US dollars.

PCR is a terrifying monster. It may be the first bombshell in the field of biotechnology, and the market it ultimately created is 100 billion US dollars. Historically, the technology patent represented by PCR is worth US$3 billion.

The controversial high-temperature resistant polymerase is not included.

Now, Yang Rui has made up for the shortcomings of high-temperature polymerase resistance, and his profits may rise sharply.

In his heart, Yang Rui had to apply for a patent at all costs.

However, it is always a false proposition at all costs. Money is the hard truth, and funds are always a bottleneck.

Yang Rui doesn't have millions of dollars in his hands.

Recently, Huarui Laboratory has spent money like water, but he dared not break it... Although the PCR experiment can apply for patents, it is still a long way from the complete academic completion. It still needs to continue to invest and there is no return in the short term. He will apply for more patents in the future, including PCR patents, and maybe Huang Mao and others have achieved results, and money is indispensable everywhere.

Enterprises will have capital chain problems, and laboratories will also have them.

Yang Rui's income is only Jielikan's dividend.

Once every three months, now you can get millions of dollars when you are too high, and only seven or eight hundred thousand when you are too low.

If this money is spent on personal life, the rich and rich don’t know how to spend it, and they can buy a Ferrari in a few days.

However, I don’t know how many things are expensive in the laboratory than Ferrari…

Yang Rui also held his forehead and said nothing.

"Mr. Yang Rui, you should also pay attention to the issue of patent disclosure. There are only a few major patent countries in the world, such as the United States, that do not have a patent disclosure system. But if you want to apply for a patent in multiple countries, you need to disclose the patent content. Anyone can search and find it. Once it is found, your technology may face competition." Yue Ting knew that Yang Rui's research was not completely completed, so he wanted to persuade him from this perspective.

Yang Rui said without thinking: "Others can't do it faster than me. Even if it is made public, they will not have time."

“But the dispute may increase costs.”

"There is no way, you can't just not apply for a patent because of this. Mr. Yue, I would rather spend all my money on PCR projects, so please worry..."

Yang Rui said this. As a lawyer, Yue Ting nodded and said, "Okay, I will complete the preparation and application work as soon as possible. You can find the public record in a maximum of one month."

"That is to say, I have at most one month left before I publish my patent?"

"Maybe only twenty days, if our application goes smoothly, we are professional patent lawyers and much faster than ordinary patent firms." Yue Ting was quite proud of this.

Yang Rui nodded slightly and said, "So far, I have been carrying out the project independently. Now that the original stage is over, I will enter the verification and improvement stage next. I am going to let the laboratory employees intervene. Is this appropriate? It won't affect the patent application work."

"Of course not." Yue Ting laughed.

Huarui's company lawyer also explained: "The employees have signed strict confidentiality agreements and have given up their relevant demands, so you can rest assured."

"I hope both of you will conduct another verification independently."

The company lawyer was a little unhappy, but he could only say: "I will take a copy to Mr. Yue."

"Independent review. If you have any questions, please report to me separately. It doesn't matter if there are loopholes in the previous contract. We can sign it now. I don't want others to intervene and there will be another loophole."

"You really should be a lawyer." Yue Ting disagreed with Yang Rui's caution, but he understood Yang Rui's importance to this matter and corrected his attitude.

For patent lawyers, they do not need to judge the value of the patent, and the employer's attitude determines everything. If the employer feels that he has invented the fragrant law, then what the patent lawyer needs to do is to protect the fragrant law without rating the fragrantness of the illegal law.

"Don't be afraid of wasting paper, the contract must be strict." Yang Rui reminded again.

This is a Nobel Prize-level achievement, and I don’t know how many colleagues in the laboratory were suing him. When Waxman discovered streptomycin, he was sued by his doctoral student Saz, who was the direct discoverer of streptomycin strains. In the end, the two settled out of court. Rutgers University issued a statement admitting that Saz was a co-discoverer of streptomycin in the legal and scientific sense of streptomycin, and gave Saz $120,000 in foreign patent income and 3% of patent income...

The academic community naturally disagrees with this. Sazz is nothing more than a head dog under Waxmann. There are 50 scientific research dogs in Waxmann's laboratory. After Waxmann took the correct screening, streptomycin may be discovered in any of the fifty scientific research dogs. It is nothing more than a matter of time.

There was nothing Saz's case with the later Nobel Prize. No scholar recognized the so-called co-discoverer in the scientific sense.

In the end, Saz had no place in the academic world, but he did indeed take away the patent share.

Yang Rui didn't want such a thing to happen to him.

When he was studying for a master's degree, there were actually many graduate students and doctoral students like Saz around him. When everyone was drunk, they would say, "I did all the work, but the results were from the boss, and the first author was from the boss... unfair!"

Yang Rui is an appointee of this injustice. Workers deserve respect, but workers are not competitive and have no right to receive praise for the results produced by intellectual activities.

The physically labored dog in the world of scientific research is not even considered a human, so how can it be qualified to get prizes and money?

Since Saz and Waxman, laboratories in various countries have also updated laboratory codes and contracts, and there are countless templates. Yue Ting and the company lawyers understand Yang Rui's psychology and are busy with each other.

That night, Yue Ting and the company lawyer met with Yang Rui respectively to modify the contract.

The next morning, after Huang Mao and others re-signed the contract, they began to participate in the PCR project.

They have indeed not participated in the discovery of PCR, and it is natural to give up relevant rights. In addition, they will not realize the powerful potential of PCR like Yang Rui.

At Yang Rui's request, in addition to Huang Mao and Tu Xian continuing their original projects, Wang Xiaoyun, Wei Zhenxue, Li Wenqiang, Duan Bo and Zhang Xuetong all joined the PCR project team one after another.

Their work is to complete a PCR experiment with the highest demanding "golden standard".

The golden guideline requires amplification of a single copy of a gene from 1 microgram of human DNA.

This will be a long and arduous process, for the first-generation PCR technology, for Li Wenqiang and others who have just been exposed to PCR, and for Zhang Xuetong, who is responsible for the production of raw materials such as oligonucleotides.

Yang Rui began to write papers independently.

Unlike the potassium ion channel project, PCR technology is simple, simple and perfect, and has a long foundation.
Chapter completed!