The original PCR technology is mixed, which is equivalent to high-precision spicy hotpot.

A bunch of DNA is selected from it and must be properly placed in the test tube. Immediately afterwards, a pile of test tubes are put into a high-temperature water bath pot. After pinching the stopwatch, it is then put into the high-temperature water bath pot, and then the low-temperature water bath pot for dozens of seconds.

Different times and temperatures will have different results, and the same action often needs to be repeated six times or more than seven times. Before there is no high-temperature resistant polymerase, new polymerase needs to be added between each action.

Such PCR technology is like computer technology in the 1940s, with a complex and precise and low fault tolerance. While people see its prospects, they also look at its shortcomings, and think that shortcomings will accompany each other.

There will always be disadvantages, but the degree will vary.

Yang Rui decided to make the first version of PCR less disadvantages, so that everyone can see the convenience of PCR, look forward to the prospects more, and pay less attention to details.

This may be a difficult choice for other companies. I don’t know how much resources you need to consume, how long it takes, and how much risk you take... After all, it’s easier to do things like doing, and it’s better to do it if you already have inspiration. If you don’t have inspiration, you will inevitably be anxious.

But for Yang Rui, it would be too simple to make PCR technology a little more advanced, just a little bit.

Taking action is not Yang Rui's strength. Yang Rui thought about it and found that he found Zhang Xuetong, first described his request, and then said: "I think that if changing multiple water bath pots into one, the most troublesome problem will be solved.

Zhang Xuetong thought with his head covered, and was stunned for a moment, saying, "There are several water baths with their own temperatures. How to use them to change them to one? None of them can be missing when heating or annealing."

Yang Rui didn't talk about the solution first, but instead said: "Let's talk about the results first. If a few water bath pots are changed to one, isn't the operation easy?"

"Then sure, first of all, there is no need to move the test tube. In the past, pinching the stopwatch to pick up the test tube, it turned into pinching the stopwatch to change the temperature." Zhang Xuetong said and asked, "Can the temperature of the water bath pot be exchanged?"

"Yes." Yang Rui said affirmatively: "If I have a good impression, there should be a water bath pot that can control the gradient temperature."

"A water bath pot that controls the temperature gradient... is a water bath pot that can quickly change temperature?" Zhang Xuetong quickly understood and frowned: "This is not easy."

"It won't be too difficult. I guess there is a finished product. If not, we will find a way to change it." This is an extremely simple improvement that modern technology has long made. Yang Rui didn't know who invented the earliest version of the automatic temperature-changing water bath pot, but at the latest in the early 1990s, this water bath pot liberated the PCR of heavy physical labor.

The precise problem is left to the machine to control, and the most complex and demanding physical strength and energy will be solved.

The original PCR device was actually that simple, a water bath pot that would change temperature, replacing multiple water bath pots.

As for the water bath, it is just a cylinder that can boil water and maintain water temperature.

After the technology that won the Nobel Prize finally became a finished product, it is not much more complicated than a spicy hot stall. The revised PCR technology is simpler, and the setting operation is slightly more complicated than the oven.

Countless people will say when they see the final version of PCR: Why didn’t I expect it?

Zhang Xuetong also felt the same way and touched his chin and said, "If there is really a quick automatic temperature-changing water bath, your method is really good... I think it is reliable, so I'll check the literature?"

"Okay, you go and check the documents. I'll ask someone to search for patents to see if any company has made it." Colleges and universities are active promoters of the Internet and computers. For colleges and universities, the cost of information query is extremely high, and it's not OK to not check it.

Documents can be checked through libraries. For example, Peking University Library has a dedicated person to do this. Patent search is also a dedicated person in large patent offices, but the fees are not expensive.

In fact, as far as the current price is concerned, only researchers like Yang Rui, who are like the head of a laboratory, have the money to search for patents or something. Ordinary researchers have neither money nor want to do such things.

It’s useless, especially researchers from universities outside Beijing. They are extremely troublesome to check a document, and it is really not easy to write a paper. Some people only have a few dollars a year, let alone hire a special company to check patents, the money they make is very tight when making calls.

However, Yang Rui was a generation used to outsourcing. By the time he was in graduate school, many experiments were not completed in a laboratory. For example, when he had to use a microscope with a magnification of tens of millions of magnifications, the laboratory could not afford a machine, and the school did not, so he might as well ask a unit with such a machine to take photos. After all, no one likes to borrow machines and solve things that can be solved with money, and no one is willing to speak.

In addition to the equipment that does not have, there are many experiments that are difficult to operate. Some experiments take more than half a year to learn, or they are very resource-intensive. Teachers are too lazy to teach, so it is better to outsource them directly to outside biotech companies. Not only does the cost are low, but they don’t have to bear the bad reputation of “exploitation”.

After entering the 10s, many teachers who could only recruit master's students but not doctoral students were becoming more and more accustomed to doing experiments by themselves. The master's students in the 10s were all pure newcomers. Their main job in the undergraduate stage was to take the postgraduate entrance examinations and rarely went to work in the laboratory, while the work in the laboratory became more and more difficult. Many teachers with master's guidance brand felt that teaching people was troublesome, so it was better to do it yourself, just treating graduate students as bottle-washing essence-the upper academic community has always been free after the reform and opening up, and it doesn't matter if they say whatever they want and do what they want to do, so that students can become essence.

In the next few days, Zhang Xuetong tried to make a quick-warming water bath pot.

This thing is not difficult, and there is no strong patent barrier. Most of the related patents have expired, and the patent-owned companies have not continued to do similar research and remediation.

After all, before the PCR era, water bath pots that could quickly change temperature were also a dragon-slaying technique, and there were very few applications.

This is the beauty of science. Some scientists will inadvertently create a dragon, and some scientists will inadvertently invent the art of dragon slaying. The most interesting thing is that scientists who invented the art of dragon slaying often invented creations that predated the dragon slaying.

When the original PCR was made, there was already a quick-changing warm water bath, but no one expected to merge the two. The private company where the PCR patent was located had not considered it, and the invention company that quickly changed warm water bath may not even know about PCR.

Under Yang Rui's instructions, Zhang Xuetong made the PCR instrument almost two or three years in advance, and with the help of a patent lawyer, he applied for a lot of patents in the name of Huarui Laboratory.

The Chinese in the laboratory do not care about patent issues, they just think that the new PCR instrument is quite useful, and both of them praise Zhang Xuetong.

"Save at least 50% of your energy." Li Wenqiang was sore in his experiments, and he particularly liked the new equipment.

Although it looks a little ugly, it is indeed easy to use.

Zhang Xuetong had a smile on his face, and felt that the value of life had been reflected to the greatest extent. He even said in a joke: "More than 50%, I think it is at least 80%.

"Eighty percent of the money will be 80%, and there will be no reward anyway." Li Wenqiang didn't care.

Duan Bo, who was selected at the same time as them, quipped: "Eighty percent of them are 80 points, and it was not worthy of reward."

"Why is it 80 points to save 80% of the effort? Could it be 90 points to save 90% of the effort?" Zhang Xuetong looked angry and was still making experimental records in his hands.

Wei Zhenxue, who was beside him, silently said: "If my son scored 90 points in the exam, I will have to beat him to death."

Li Wenqiang and Zhang Xuetong were speechless immediately. It turns out that we are all your sons?

As the only female researcher in the laboratory, Wang Xiaoyun asked in fear that the world would be in chaos: "Old Wei, how many points will you beat me?"

"Of course it will take 100 points." Wei Zhenxue said naturally.

"100 points? It's over." Wang Xiaoyun smiled.

Wei Zhenxue was puzzled: "Why is it over?"

"Because zero cannot be divided." Li Wenqiang shook his head.

Wei Zhenxue suddenly reacted and said with a "Oh" sound, "That's right, saving 80% of the energy is 80 points, saving 90% of the energy is 90 points, and 100 points, and saving 100 points. In this way, you can't get 100 points."

"Yes." Zhang Xuetong replied casually.

"Yes." Wei Zhenxue sighed and said, "Fortunately, you two turtle sons are not in my hands. Otherwise, you will be in the 90s every time, and I will have to discount your legs."

Li Wenqiang was stunned for a moment, feeling that he was at a loss, but he didn't know how to refute it.

...
Chapter completed!