Chapter 650: The clinical paradox of xenotransplantation(2/2)
Hurry up and think of a solution!
He complained silently in his heart, so he patted Ding Mian on the shoulder hard, trying to wake him up from his wandering state.
"Director Ding, did you hear what Dean Fang said? Should we report the current difficulties to the General Health Director and then arrange overseas clinical trials as soon as possible?"
"For example, Eagle Country and some countries in Europe recognize the existence of brain death. Can they recruit brain-dead volunteers? After completing clinical trials and obtaining proof of safety and effectiveness, they can then launch formal human clinical trials in the country?"
"What do you think?"
After Huang Qin finished speaking, he looked at Dean Fang again: "What do you think?
"Is the idea I just thought feasible?"
Dean Fang showed admiration: "Yes, this plan is good and the feasibility is quite high."
"In the gap between animal experiments and clinical practice, brain-dead remains must be used as a transition model."
"This can avoid cross-species disease risks and solve the fundamental problem that xenotransplantation cannot enter the clinical research stage."
"I support you very much. The Cleveland Clinic in Eagle Country has a close relationship with us. As long as we tell them, I believe they will be willing to carry out follow-up clinical cooperation with Sanqing on our behalf."
At this time, a voice suddenly came out, interrupting the conversation between the two.
"Would it be better if we just connected the kidneys to the blood vessels in the legs of brain-dead patients and performed cardiopulmonary bypass dialysis instead of organ transplantation?"
"Huh?" Huang Qin turned his head in shock and saw Ding Mian with a deep look on his face.
Before he had time to react, the other person continued talking.
"First of all, let's make it clear that we are using human kidneys from pigs, which have a very high safety factor and are not at the same level of safety as pig kidneys."
"Secondly, we only connect the blood vessels and the kidneys are outside the body. This can maintain controllability to the greatest extent. Once any problem occurs, we will immediately cut off the blood vessel connection without causing serious consequences."
"Finally, our connection time will not be long, no more than 48 hours at most. We are just verifying functionality and acute immune rejection to facilitate subsequent improvements."
"In such a short period of time, it will not cause any harm to the body of the brain-dead patient, and there will be no change in appearance. It should be easier for the patient's family to accept it."
"Of course, this is also a transitional plan. After all, it will take several months for overseas clinical arrangements to be completed. We can obtain some detailed clinical data before then. What do you think?"
Dean Fang was stunned for a moment after hearing these words. When Ding Mian finished speaking, he couldn't help but slap his thigh and let out a cheer.
"Second, Xiao Ding, you are still smart. I think this method is feasible and does not violate the regulations. I will try my best to communicate with the family."
"Hey, even if the patient is brain dead, as long as the heartbeat and breathing have not stopped, to the family members, he is still a living person."
"It would be difficult for any family member to accept that their organs should be taken away. This is also human nature."
"However, it is just to connect an organ outside the body to verify the functionality and safety. I don't think the family members will be very objectionable."
"Of course, subsequent compensation such as medical expenses and the like are unavoidable."
Huang Qin understood instantly and said quickly: "That's no problem. In order to thank the patient for his contribution to medical research, we will bear the life support and medical expenses during the period of brain death. We will never embarrass the family."
Dean Fang nodded with satisfaction.
Chapter completed!